
产品货号:
Z37000
中文名称:
Hu CD83 Purified抗体
英文名称:
Anti-Hu CD83 Purified Antibody (Clone#HB15e)
产品规格:
0.1mg(C100)
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-Hu CD83 Purified Antibody (Clone#HB15e) |
指标别名 | B cell activation protein;BL11;CD83;CD83 antigen;CD83 molecule;Cell surface protein HB15;HB15;hCD83 |
克隆性 | Monoclonal |
检验物种 | human,primate |
应用范围 | FCM,IHC-F |
基因名称 | CD83 |
克隆号 | HB15e |
抗体来源 | Mouse |
免疫原 | Human CD83-transfected Cos cells.The mouse monoclonal antibody HB15e recognizes an extracellular epitope of CD83,a 40~45kDa type I glycoprotein expressed on mature dendritic cells. |
计算分子量 | 23kDa |
成分 | Phosphate buffered saline (PBS),pH7.4,15mM sodium azide |
纯化方式 | Purified by protein-A affinity chromatography. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | Store at 2~8℃.Do not freeze. |
背景资料 | CD83 is a 40~45kDa heavily glycosylated type I cell surface glycoprotein of immunoglobulin family.It is expressed on the surface of mature dendritic cells,Langerhans cells in the skin,and interdigitating reticulum cells in the lymphoid tissues.Low expression of CD83 has been reported in activated T and B cells.Cytoplasmic expression of CD83 can be detected also in monocytes and macrophages.CD83 is involved in modulation of antigen presentation.Soluble CD83 has immunoregulatory functions,it is able to down-regulate dendritic cell maturation and stimulation of T cells.In the developing immune system,release of soluble CD83 from dendritic cells upon stimulation by gram-positive or gram-negative bacteria has anti-allergic effect.Herpes simplex virus,on the other hand,causes CD83 degradation in mature dendritic cells. |
Uniprot ID | Q01151 |
基因名全称 | CD83 molecule |
蛋白名全称 | CD83 antigen |
推荐稀释比 | Flow cytometry:1~4μg/mL,Positive control:peripheral blood-derived dendritic cells. Immunohistochemistry (frozen sections):acetone fixation. |
相关搜索:Hu CD83 Purified抗体,Hu CD83 Purified单抗,Anti-Hu CD83 Purified Antibody (Clone#HB15e)